Sale!

Buy 5 mg Saphris sublingual tablet online

$1,263.10

QuantityPer unitPrice
60 (6 x 10 each)$21.05$1,263.14
100 (10 x 10 each)$20.99$2,098.88

Buy 5 mg Saphris sublingual tablet online. Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder. It was chemically derived via altering the chemical structure of the tetracyclic antidepressant, mianserin. Buy 5 mg Saphris sublingual tablet online

What is Saphris and how is it used?

Saphris is a prescription medicine used to treat the symptoms of Schizophrenia and Bipolar Disorder. Saphris may be used alone or with other medications.

Saphris belongs to a class of drugs called Antipsychotics, 2nd Generation.

It is not known if Saphris is safe and effective in children younger than 10 years of age.

What are the possible side effects of Saphris?

  • very stiff (rigid) muscles,
  • high fever,
  • sweating,
  • confusion,
  • fast or uneven heartbeats,
  • lightheadedness,
  • tremors,
  • twitching,
  • uncontrollable movements of your eyes, lips, tongue, face, arms or legs,
  • slow heartbeats,
  • lightheadedness,
  • breast pain or swelling,
  • nipple discharge,
  • trouble swallowing,
  • sudden weakness,
  • ill feeling,
  • fever,
  • chills,
  • sore throat,
  • swollen gums,
  • painful mouth sores,
  • skin sores,
  • cold or flu symptoms,
  • cough,
  • sudden numbness or weakness,
  • sudden severe headache,
  • slurred speech, and
  • problems with vision or balance

Get medical help right away, if you have any of the symptoms listed above.

The most common side effects of Saphris include:

  • dizziness,
  • drowsiness,
  • feeling tired,
  • restlessness,
  • inability to sit still,
  • numbness or tingling inside or around your mouth,
  • ulcers, blisters, swelling, or peeling of your gums,
  • nausea,
  • altered sense of taste,
  • increased appetite, and
  • weight gain

Tell the doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Saphris. For more information, ask your doctor or pharmacist.

DESCRIPTION

SAPHRIS contains asenapine maleate which is an atypical antipsychotic that is available for sublingual administration. Asenapine belongs to the class dibenzo-oxepino pyrroles. The chemical designation is (3aRS,12bRS)-5Chloro-2-methyl-2,3,3a,12b-tetrahydro-1Hdibenzo[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate (1:1). Its molecular formula is C17H16ClNO•C4H4O4 and its molecular weight is 401.84

Asenapine maleate is a white to off-white powder.

SAPHRIS, black cherry flavor, is supplied for sublingual administration in tablets containing 2.5 mg, 5 mg or 10 mg asenapine; inactive ingredients include gelatin, mannitol, sucralose, and black cherry flavor.

INDICATIONS

SAPHRIS is indicated for:

  • Schizophrenia in adults [see Clinical Studies]
  • Bipolar I disorder
    • Acute monotherapy of manic or mixed episodes, in adults and pediatric patients 10 to 17 years of age
    • Adjunctive treatment to lithium or valproate in adults
    • Maintenance monotherapy treatment in adults

DOSAGE AND ADMINISTRATION

Administration Instructions

SAPHRIS is a sublingual tablet. To ensure optimal absorption, patients should be instructed to place the tablet under the tongue and allow it to dissolve completely. The tablet will dissolve in saliva within seconds. SAPHRIS sublingual tablets should not be split, crushed, chewed, or swallowed. Patients should be instructed to not eat or drink for 10 minutes after administration

Schizophrenia

The recommended dose of SAPHRIS is 5 mg given twice daily. In short-term controlled trials, there was no suggestion of added benefit with a 10 mg twice daily dose, but there was a clear increase in certain adverse reactions. If tolerated, daily dosage can be increased to 10 mg twice daily after one week. The safety of doses above 10 mg twice daily has not been evaluated in clinical studies

Bipolar I Disorder

Acute Treatment Of Manic Or Mixed Episodes

Monotherapy in Adults: The recommended starting and treatment dose of SAPHRIS is 5 mg to 10 mg twice daily. The safety of doses above 10 mg twice daily has not been evaluated in clinical trials

Monotherapy in Pediatric Patients: The recommended dose of SAPHRIS is 2.5 mg to 10 mg twice daily in pediatric patients 10 to 17 years of age, and dose may be adjusted for individual response and tolerability. The starting dose of SAPHRIS is 2.5 mg twice daily. After 3 days, the dose can be increased to 5 mg twice daily, and from 5 mg to 10 mg twice daily after 3 additional days. Pediatric patients aged 10 to 17 years appear to be more sensitive to dystonia with initial dosing with SAPHRIS when the recommended escalation schedule is not followed. The safety of doses greater than 10 mg twice daily has not been evaluated in clinical trials.

Adjunctive Therapy in Adults: The recommended starting dose of SAPHRIS is 5 mg twice daily when administered as adjunctive therapy with either lithium or valproate. Depending on the clinical response and tolerability in the individual patient, the dose can be increased to 10 mg twice daily. The safety of doses above 10 mg twice daily as adjunctive therapy with lithium or valproate has not been evaluated in clinical trials.

For patients on SAPHRIS, whether used as monotherapy or as adjunctive therapy with lithium or valproate, it is generally recommended that responding patients continue treatment beyond the acute episode.

Maintenance Treatment Of Bipolar I Disorder

Monotherapy in Adults: Continue on the SAPHRIS dose that the patient received during stabilization (5 mg to 10 mg twice daily). Depending on the clinical response and tolerability in the individual patient, a dose of 10 mg twice daily can be decreased to 5 mg twice daily. The safety of doses above 10 mg twice daily has not been evaluated in clinical trials

HOW SUPPLIED

Dosage Forms And Strengths

  • SAPHRIS 2.5 mg tablets, black cherry flavor, are round, white to off-white sublingual tablets, with a hexagon on one side.
  • SAPHRIS 5 mg tablets, black cherry flavor, are round, white to off-white sublingual tablets, with “5” on one side within a circle.
  • SAPHRIS 10 mg tablets, black cherry flavor, are round, white to off-white sublingual tablets, with “10” on one side within a circle.

Storage And Handling

SAPHRIS (asenapine) sublingual tablets are supplied as:

2.5 mg Tablets, black cherry flavor

Round, white to off-white sublingual tablets, with a hexagon on one side. Child-resistant packaging

Box of 60 6 blisters with 10 tablets NDC 0456-2402-60

Hospital Unit Dose

Box of 100 10 blisters with 10 tablets NDC 0456-2402-63

5 mg Tablets, black cherry flavor

Round, white to off-white sublingual tablets, with “5” on one side within a circle.

Child-resistant Packaging

Box of 60 6 blisters with 10 tablets NDC 0456-2405-60

Hospital Unit Dose

Box of 100 10 blisters with 10 tablets NDC 0456-2405-63

10 mg Tablets, black cherry flavor

Round, white to off-white sublingual tablets, with “10” on one side within a circle.

Child-resistant Packaging

Box of 60 6 blisters with 10 tablets NDC 0456-2410-60

Hospital Unit Dose

Box of 100 10 blisters with 10 tablets NDC 0456-2410-63

Storage

Store at 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C and 30°C (59°F and 86°F) [see USP Controlled Room Temperature]. Buy 5 mg Saphris sublingual tablet online 

Category:

Reviews

There are no reviews yet.

Only logged in customers who have purchased this product may leave a review.