Buy 15 mg aripiprazole oral tablet disintegrating online
Buy 15 mg aripiprazole oral tablet disintegrating online. Aripiprazole is an atypical antipsychotic that is offered under the brand names Abilify and Aristada, among others. It’s most commonly used to treat schizophrenia and bipolar disorder. Other use include treating major depressive illness, tic disorders, and autism-related irritability. It can be given orally or via injection into a muscle. A Cochrane study discovered evidence of efficacy in the treatment of schizophrenia.
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The major goal of this study was to investigate the pharmacokinetic characteristics and relative bioavailability of two 15-mg aripiprazole formulations in healthy middle-aged Korean volunteers (an orally disintegrating tablet [ODT] as the test drug and a conventional tablet as the reference drug).
Methods: A randomised, open-label, single-dose, 2-sequence, 2-period crossover trial was undertaken in a sample of healthy middle-aged Korean participants. Blood samples were obtained at specific time intervals from 0 to 240 hours after administration of a single dosage of a 15-mg aripiprazole standard tablet with 240 mL water or an aripiprazole 15-mg ODT without water. Aripiprazole concentrations in plasma were determined using the LC-MS/MS technique of detection. Data on pharmacokinetic parameters were collected, and using an ANOVA model, the 90 percent CIs of the ratios of the geometric means of the parameters were calculated from the logarithmically transformed data.
Findings: Thirty-nine healthy middle-aged Korean subjects (mean age, 52.7 years; mean height, 167 cm; mean weight, 67.6 kg) were enrolled in the study; 33 of them finished it (29 male subjects and 4 female subjects). Cmax, AUC0-last, and AUC0-values had 90 percent CIs of 0.95 to 1.14, 0.98 to 1.09, and 0.97 to 1.08, respectively, for the geometric means ratio (test drug/reference drug). All of the participants who had adverse events recovered without repercussions, and there were no significant adverse events reported.
In these healthy middle-aged Korean subjects, the pharmacokinetics of aripiprazole were identical for the ODT and regular tablet of 15 mg aripiprazole. Patients who have trouble swallowing tablets without water should find the aripiprazole ODT formulation to be a convenient alternative. Buy 15 mg aripiprazole oral tablet disintegrating online
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